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Initially used as a textile dye, its medicinal potential was soon realized, leading to its widespread adoption in treating methemoglobinemia, urinary tract infections, and even as an antiseptic agent

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Because the most translatable animal models are humanized constructs rather than the exhaustively validated wild-type rodents behind the peptide literature, evidence synthesis should lean comparatively more on the human trials and be cautious about importing conclusions from peptide rodent studies

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