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The GLP-1-activated neurons in the brain also limit appetite for a while after a large meal (e.g., the thought of eating is unappealing for many hours after pigging out on pizza).[ref] Stress-related appetite suppression: Additionally, the GLP-1 neurons activate during times of acute stress to suppress appetite

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Peristalsis, segmentation, and the myenteric reflex

For the majority of patients, any reaction that occurs is mild and temporary, usually fading within a few hours to a few days

Yes, but with important caveats