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Description
15,272 GLP-1RAs and joint disorders GLP-1RAs in OA GLP-1R expression was detected via immunohistochemistry in articular chondrocytes from both normal and osteoarthritic individuals

Islet beta-cell secretion determines glucagon release from neighbouring alpha-cells
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A large meta-analysis of 45 RCTs recently found that compared with placebo or other interventions, GLP-1RAs did not increase the risk of thyroid cancer, hyperthyroidism, hypothyroidism, thyroiditis, thyroid mass, and goiter [69]

Efficacy and Safety of Glucagon-Like Peptide-1 Receptor Agonists on Body Weight and Cardiometabolic Parameters in Individuals With Obesity and Without Diabetes: A Systematic Review and Meta-Analysis, Endocrine Practice, Volume 30, Issue 2, 2024, Khan SS, Ndumele CE, Kazi DS

Only case reports, case series, retrospective chart reviews, open-label trials, and randomized controlled trials (RCTs) were considered
