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[DOI] [PMC free article] [PubMed] [Google Scholar] Harris PE, Ferrara C, Barba P, Polito T, Freeby M, Maffei A

The amylin signaling pathway is distinct from and complementary to GLP-1 receptor signaling, as amylin primarily influences hedonic appetite pathways (reward-driven eating) while GLP-1 primarily affects homeostatic appetite regulation

Obviously, the suggested conclusions were not sensitive to minor or even major changes in the methodology

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This gut-derived hormone enhances glucose-dependent insulin secretion, suppresses glucagon secretion, delays gastric emptying, and promotes satiety