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Considerations for employers who are thinking about covering GLP-1 drugs for weight loss.

OR2=0.21 [95% CI 0.050.92], P2=3.89102)

Sequence: EGTFTSDVSSYLEGQAAKEFIAWLVKGR(NH2)

By including all English-language studies on muscle mass loss during GLP-1RA therapy in T2D and obesity from major scientific databases and clinical trial registries, this narrative review synthesizes the current knowledge on the epidemiology and mechanisms of muscle loss in diabetes and obesity, with a focus on the impact of GLP-1RAs therapy

A mitochondrial switch ("SLC25A45") controls whether mitochondria burn fat or carbohydrate, and removing it (in mice) makes GLP-1 drugs stop working for fat loss entirely