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Women planning pregnancy should discuss discontinuation timing with their healthcare provider, typically allowing approximately 25 days (five half-lives) for tirzepatide to be substantially eliminated from the body before conception

GERD further exacerbates erosion. Khan says this erosion can have a ripple effect, triggering oral sensitivity, discolored teeth, and teeth that look smaller
Slowing Gastric Emptying By slowing the stomachs emptying process, these medications promote a feeling of fullness

Your healthcare provider should start you at the lowest available dose and increase it slowly over time

The Protonix case defines the at-risk launch decision framework
