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Dual GLP-1/GIP agonists, such as tirzepatide, have been introduced, and they offer greater weight loss and potential cardiovascular advantages [14]

Case subjects were meticulously matched with up to 20 control subjects, considering variables such as age, sex, and the length of diabetes, using the risk-set sampling procedure

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A study on whether and how the activation of GLP-1R affects proliferation and apoptosis of human pancreatic cancer cells has demonstrated that GLP-1RAs might activate cAMP in a GLP-1R-dependent manner, subsequently inhibiting the AKT and ERK1/2 signaling pathways, hence inhibiting the growth of transplanted tumors in vivo , as well as inducing apoptosis and inhibiting the proliferation of a human pancreatic cancer cell line in vitro ( 225)