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Description

The composition of GLP-1 prescribing changed markedly over the period

However, given the neutral effect of GLP-1 RAs on surrogate HF outcomes in HFrEF and a potentially increased risk of arrhythmias and HF-related hospitalisations, conducting further large-scale trials in the HFrEF cohort seems complicated

Serious but rare side effects include pancreatitis, gallbladder problems, and allergic reactions

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