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Regardless, they highlight the importance for screening for suicidal ideations in patients with obesity and diabetes so that proper support can be given to those at risk, and to ensure that studies like ours that evaluate long-term effects of semaglutide or other medications can properly evaluate potential suicidal risk. Among adults with type 2 diabetes who had longer follow-up data available, those receiving semaglutide had a lower risk for suicidal ideation at 1 year (HR = 0.39

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Trimethoprim-sulfamethoxazole has no direct interaction with semaglutide

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