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Additionally, expanded insurance coverage and favorable regulatory approvals are accelerating market adoption, while ongoing research and development of patient-friendly, long-acting formulations is supporting long-term growth

Serious and Rare Adverse Effects of Incretin Mimetics While the vast majority of glp-1 peptides side effects are mild and gastrointestinal in nature, researchers must remain vigilant regarding rare but severe adverse events that have been flagged in pharmacovigilance databases and animal studies

doi: 10.1056/NEJMoa1612917 81 RuffCTBaronMImKODonoghueMLFiedorekFTSabatineMS

Traditional pharmacotherapies targeting monoamine systems have shown limited efficacy, prompting the investigation of alternative neuromodulatory systems such as the GLP-1 pathway

A double-blind-randomized controlled trial