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GLP-1 Medications The primary difference lies in mechanism: metformin makes your existing insulin work better, while GLP-1 agonists make your pancreas secrete more insulin and suppress your appetite through brain-level signaling

( 10.1001/jama.2023.24945) [DOI] [PMC free article] [PubMed] [Google Scholar] Ast J, Arvaniti A, Fine NHF, Nasteska D, Ashford FB, Stamataki Z, Koszegi Z, Bacon A, Jones BJ, Lucey MA, et al

[DOI] [PubMed] [Google Scholar] 19.Frias J.P., Nauck M.A., Van J., Kutner M.E., Cui X., Benson C., Urva S., Gimeno R.E., Milicevic Z., Robins D., et al

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