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Additionally, some individuals may be taking concomitant medications that affect sleep architecture

The cardiovascular benefits appear to be a class effect, with all GLP-1 agonists showing benefit, though the magnitude varies between specific medications

FDA Certification

This review will use the term MASLD, defined as the presence of hepatic steatosis with no other discernible cause, in conjunction with at least one cardiometabolic risk factor (CMRF), such as type 2 diabetes mellitus (T2DM), obesity, hypertension, or dyslipidemia

Weeks 5-12: Building momentum As retatrutide increases to 2 mg and then 4 mg, and cagrilintide is introduced at 0.25 mg, appetite suppression becomes noticeable