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According to the Pharmacotherapeutic Compass, both medicines are indicated as an adjunct to a calorie-restricted diet and increased physical activity in adults with a BMI of 30 or higher, or 27 or higher in the presence of weight-related comorbidities

The relationship between dose and effect follows a sigmoid curve, meaning small potency losses at certain dose points might barely matter while the same percentage loss at other points could significantly reduce effectiveness

Importantly, the lack of plant-based foods in the CD also prevents intake of important phytochemicals, dietary fiber, and essential micronutrients

The bias of the articles was classified as follows: low risk of bias, unclear risk of bias, and high risk of bias

Ozempic (semaglutide), on the other hand, is a glucagon-like peptide-1 receptor agonist, or GLP-1