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The question is when and how much

This mechanism makes semaglutide valuable for diabetes management even when weight loss is modest

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Patients with proliferative retinopathy should be referred for treatment according to standards of care established by pivotal studies such as the Diabetic Retinopathy Study, the ETDRS, and the Diabetic Retinopathy Clinical Research Network (DRCR) Protocol S ( Figure 1 )

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