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Figure 3 Discussion In this large-scale real-world cohort study emulating a target trial, we evaluated the comparative dermatologic outcomes associated with initiation of GLP-1 receptor agonists versus DPP-4 inhibitors among patients with T2DM

Clinical studies show an average of 5-10% weight loss by month 3, with continued progress over time

It is estimated that many as 50% to 75% of people who take a GLP-1 discontinue it within a year

The long-term safety profile will not be fully established until larger and longer trials are completed

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