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For a patient at 113 kg, that is 15 kg over 72 weeks, enough to reverse prediabetes in many cases, meaningfully reduce blood pressure, and improve sleep quality

"By opening up about her own health, Serena is opening doors for millions of people who have felt shamed for needing support to lose weight," said Zach Reitano, co-founder and CEO of Ro

Clinical trials have shown weight loss of up to 22.5% in some individuals

Doctors may consider increasing the dose to 7.2mg if weight loss remains insufficient, but only once the higher dose is licensed and available in the UK

The simplicity of the toolkit belies the importance of the technique