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GLP-1s often lead to 3050 pounds of weight loss, while surgery can result in far greater total body weight reduction, particularly in those with a BMI over 40 or severe obesity-related health issues

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Ebdrup BH, Knop FK, Ishy PL, Rostrup E, Fagerlund B, Lublin H, et al

GLP-1 users typically lose between 15% and 25% of their body weight over the course of a year, and he said the improvements some patients notice could be tied, at least in part, to the weight loss itself
