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Some debate exists about long-term use since obesity tends to be chronic, these medications likely need to be continued to maintain weight loss (as stopping leads to regain, based on observations)
Leptin responsiveness restored by amylin agonism in diet-induced obesity: Evidence from nonclinical and clinical studies
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The sample sizes for both in vitro transfection studies (Hepa1-6 and HepG2 cells) and in vivo studies (Balb/c and DIO mice) were predetermined
