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Orlistat works by blocking fat absorption in the gut and carries a documented risk of kidney stones and oxalate nephropathy, making it generally unsuitable for people with CKD or a history of kidney stones

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Social media influencers are touting a new option for popular weight loss drugs: GLP-1 patches, they say, are just as powerful as Ozempic for shedding pounds without the discomfort of needles or the hassle of getting a prescription

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Glucagon-Like Peptide 1 and Its Analogs Act in the Dorsal Raphe and Modulate Central Serotonin to Reduce Appetite and Body Weight

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PBMs thus classify them as high-cost therapies requiring careful oversight

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