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Since initiation, her hemoglobin A1c decreased from 8.6% to 5.6%, insulin therapy was discontinued, and she achieved significant weight loss, with improved liver function and laboratory parameters

GLP-1 weight loss stall explained

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The Safety, Tolerability and Efficacy of Rapid UpTitration of GuidelineDirected Medical Therapies in Acute Heart Failure (STRONG-HF) trial validated rapid up-titration strategies, demonstrating that early high-intensity GDMT implementation with structured follow-up significantly reduces 180-day mortality and readmissions
