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This is an impactful advancement in T2DM management, as some diabetics may be managing multiple injections per day if on insulin

Historically, centrally acting peptides were avoided due to concerns about neuropsychiatric side effects and bloodbrain barrier delivery

The result is a dangerous and unpredictable retention of solids in the stomach, sometimes after as long as 30 hours of fasting

Understanding Ectopic Fat Another important topic is ectopic fat

This target trial emulation study compared GLP-1RAs with two other medications used in diabetes treatment: sodium-glucose cotransporter-2 inhibitors (SGLT2is) and dipeptidyl peptidase-4 inhibitors (DPP4is)