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This dual mechanism may enhance its effectiveness in managing blood sugar and promoting weight loss

These drugs work by imitating glucagon-like peptide-1 (GLP-1), a growth hormone that triggers insulin release, reduces blood sugar levels, slows the progress of food along the intestinal track, and stimulates parts of the brain that control craving and satiety

Blood sugar control (HbA1c reduction) was also superior in the orforglipron arm

Taking your injection at night often improves tolerability since you sleep through peak nausea hours, and splitting meals into 4-6 smaller portions rather than 3 standard meals keeps your stomach comfortable

Given how destructive addictions can be, I vote for more research in this direction