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The need to consider switching or starting alternative therapies may have a significant impact on workload for primary care and community and specialist diabetes teams, and may cause people with diabetes anxiety and concern

But if youre pregnant, planning a pregnancy, or breastfeeding, the safety of tirzepatide becomes a very different conversation

10.1038/nm1168 85

Were not specifically marketing ourselves at this time as a diabetes treatment or hypertension treatment yet, she said

The primary endpoint was to determine whether orforglipron could achieve statistically significant efficacy results in improving glycemic control compared to placebo, as measured by reductions in HbA1c levels