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81 The microbiome and immune system engage in bidirectional communication, with dysbiotic microbiota from IBD patients or colitis models shown to exacerbate or induce inflammation when transferred to healthy or susceptible hosts

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The collective glucoregulatory actions of GLP1 make this peptide a potential powerful agent for the treatment of diabetes

The benefits of SGLT2i therapy also extends to CKD where there is a significantly reduced risk of decline in eGFR and progression to end stage renal failure, regardless of presence or absence of type 2 diabetes [23]