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Description
This article reviews the efficacy and safety of different strategies to initiate and intensify basal insulin, with focus on new fixed ratio combinations of basal insulin with GLP-1 RAs available for use in a single injection pen (insulin degludec/liraglutide and insulin glargine/lixisenatide).
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Summary Integrating emerging mechanistic and clinical observations, this review synthesizes current evidence from a metabolic flux perspective
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