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Compared with the other medications, people taking the GLP-1 drugs had a reduced risk for addiction: 18 per cent for alcohol, 14 per cent for cannabis, 20 per cent for both cocaine and nicotine, and 25 per cent for opioids

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When adding GLP-1-R-Antagonist Exendin (9-36), the effects of Liraglutide were reversed, indicating receptor-mediated action [13]

Herrington WG, Staplin N, Wanner C, Green JB, Hauske SJ, et al

Incretins Introduction Type 2 diabetes may result from a variety of conditions including -cell dysfunction, where insulin is not produced, and/or due to insulin resistance, in both cases leading to hyperglycemia, and complications in both small and large blood vessels (Silberstein, 2013)