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Also, anti-proliferative effects on smooth muscle cells and anti-inflammatory effects on macrophages may contribute to the protection against the development and progression of atherosclerosis [8-10]

This puts you at greater risk of illness, decreases quality of life, and makes weight loss harder to maintain

In addition, the insulinotropic effect of the dual GIP/GLP-1 receptor agonist was abrogated by GIP receptor antagonist (GIPRA) in GLP-1R null mice (63)

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