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The Bristol Myers Squibb clinical trial failed, whereas the Merck trial was successful, meaning Merck's strategic decision enabled to them to take the lead in NSCLC and ultimately Bristol Myers Squibb was never able to catch up

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Its based on the clinical trial design used in the SURMOUNT and SURPASS programs, where this gradual approach consistently produced better tolerability outcomes than faster titration

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Whether the formulation includes additional ingredients like vitamin B12 or niacinamide matters

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In the Phase III REDEFINE 1 trial, CagriSema demonstrated a 22.7% mean weight loss after 68 weeks, surpassing both monotherapies and placebo

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