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Common gastrointestinal side effects that are especially severe or do not resolve within a few weeks, such as nausea, diarrhea, constipation, or vomiting, are also common reasons for stopping the medication

In the pancreas, beta cell-specific genes, such as Ins1 and Ins2 , exhibit a significant decline in the positive control (PC) group followed by a gradual dose-dependent significant increase in the treatment groups (GS1, GS2) (Figure 6A)

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Accessed 18 February 2021 Institute of Medicine (2014) Capturing social and behavioral domains and measures in electronic health records: phase 2

GLP-1 receptor agonists slow gastrointestinal motility throughout the digestive tract, prolonging transit time and allowing more water absorption from stool in the colon