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This framework integrated evidence through the following streams: (1) Tirzepatide compared to placebo (indirect comparison): In the absence of direct tirzepatide CV outcome placebo-controlled trials, these estimates were derived by bridging direct evidence from SURPASS-CVOT with pooled data from multiple GLP-1RA-placebo trials

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LASTLY THE MAINTENAINCE DOSE CAN BE ONGOING FOR UP TO 8 MONTHS DEPENDING ON YOUR GOALS Shipping: This product can be shipped 2-Day or Overnight and does not need to be refrigerated during shipping

However, given limited data, men may consider discussing timing of conception attempts with their healthcare provider

This gradual reduction may allow patients to adapt to increasing appetite and implement behavioral strategies progressively