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Gastrointestinal side effects , particularly nausea and vomiting, are common during the initial weeks of treatment and following dose increases

Patients might need to explore alternative therapies to sustain weight loss or maintain glycemic control

While the absolute risk with Mounjaro remains very low, cases have been reported with GLP-1 receptor agonists, particularly when insulin is rapidly reduced or discontinued upon starting treatment

At the heart of their effectiveness is GLP-1, a hormone that plays a crucial role in controlling appetite and metabolism

In 2021, it was in the Top 100 most-prescribed drugs in the United States