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Alshwaiyat NM, Ahmad A, Wan Hassan WMR, Al-Jamal HAN

Another example is an extension of the STEP-1 trial, which randomised 1961 adults to either semaglutide or placebo for 68 weeks

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(2017) transplanted a variety of commensal bacteria isolated from human feces into mice and found that the mouse gut segmented filamentous bacteria and human commensal bacteria promoted the differentiation of Th17 cells in the gastrointestinal tract of mice, which induced pro-inflammatory cytokines (including IL-17, TNF-, and IL-1), as well as the production of osteoclasts, and enhanced bone resorption

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