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Tirzepatide, a dual GLP-1 and GIP receptor agonist, slows stomach emptying to regulate appetite and blood sugara mechanism that may cause heartburn or reflux in roughly 10-15% of early users

Since these medications mimic this natural hormone, they can: Reduce appetite and help manage blood sugar Help the pancreas release the right amount of insulin Slow how quickly food leaves the stomach, which helps you feel full longer Many GLP1 agonists are taken as injections

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Based on SURMOUNT-1 data, participants on the 15 mg dose were averaging roughly 15% body weight loss by around this point in the trial