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However, the miR-21 expression by the influence of curcumin is downregulated in hepatocellular cancer cells, which stimulates the expression of metalloproteinase-3 (TIMP3) and suppresses the GF-b1/smad3 signalling, resulting in the proliferating of cancer cells (Li et al., 2020)
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The progressive loss of dopaminergic neurons reduces TH levels and subsequently diminishes dopamine production
Theres research behind this, mostly starting with animal work
