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Enrolled patients were randomized to once-daily oral Wegovy 25 mg or placebo, as an adjunct to lifestyle intervention for 64 weeks

[DOI] [PMC free article] [PubMed] [Google Scholar] 133.Helmstdter J., Frenis K., Filippou K., Grill A., Dib M., Kalinovic S

Pharmacotherapy 37 , 927943 (2017)

It should be noted that the small percentage of participants (6.1% in the Harmony trial) in the subgroup with baseline SGLT-2i use may have reduced the consistency of the treatment effect estimates

it demands the sustained education of prescribers, payers and patients on the clinical value, appropriate use and innovation behind the oral delivery of biologics