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The primary actions of GLP-1 include stimulating insulin secretion from pancreatic beta cells in response to elevated blood glucose (importantly, this insulin release is glucose-dependent, reducing hypoglycaemia risk), suppressing glucagon release (which prevents the liver from producing excess glucose), and slowing gastric emptying

Kidney Int 2023;103:77281

Mayo Clinic emphasizes that muscles need recovery time to adapt and rebuild. Muscles rebuild during rest

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Specifically, the drug lowered weight by up to an average of 71.2 lbs and reduced pain by up to an average of 75.8%