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Of the estimated 2 million Americans with opioid use disorder, its unclear how many also have diabetes or weight-related conditions that could prompt them to seek GLP-1s and, given the medications price tag, how many could access them, even if they were interested

The weight-loss results at 48-weeks with the 12 mg (higher dose) retatrutide group achieved a mean weight reduction of -24.2%, while the placebo group only saw a -2.1% change

These could include other classes of medications or focusing more intensively on lifestyle interventions

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This form still works like regular semaglutide and supports those managing type 2 diabetes or weight concerns