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The share of the largest firms covering these medications for weight loss increased significantly in 2025, but many of these firms also reported higher than expected use, as well as a significant impact on prescription costs

They are not recommended for individuals with a history of certain thyroid cancers, pancreatitis, or severe gastrointestinal issues

Chou WL

(2006) Molecular physiology and pharmacology of calcitonin

In T2DM patients, a single dose of tirzepatide delayed gastric emptying with a reduced effect over time
