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Combining these agents poses unpredictable risks to glucose metabolism, as tesamorelin raises GH and can induce insulin resistance, potentially opposing retatrutide's glycaemic effects

If adverse effects outweigh benefits, prioritize safety and de-escalate

1 Introduction Type 2 diabetes mellitus(T2D) is both an endocrine and metabolic disease and the prevalence is increasing exponentially worldwide ( Prolactin (PRL) is a polypeptide hormone that is mainly synthesized and secreted by lactotroph cells of the anterior pituitary gland

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