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The semaglutide group experienced fewer serious adverse events compared to placebo ( 49.6% versus 53.8%), but more adverse events leading to discontinuation ( 13.2% versus 11.9%)

When combining GLP-1 receptor agonists with insulin or sulfonylureas, the chance of experiencing hypoglycemia (low blood sugar) goes up

The NHS recommends 6-8 glasses of fluid daily for most people, though requirements vary based on individual factors including activity level, climate, and health conditions

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Retatrutide, on the other hand, requires the most diligent titration out of the three