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[Ca 2+ ] i was measured in islets from mice expressing GCaMP6f in alpha cells

This approach strengthens the analytical toolkit to going beyond gold-standard techniques like IP-RPLC, enabling efficient tracking of both excipient- and peptide-related CQAs, which help to ensure overall drug product quality

This study also suggested that Gly 22 plays an important role in separating the two helices and allows the peptide to present a single hydrophobic surface to the membrane

And in June 2024, they updated their recommendations, now advising intensive counseling for children aged six and older with a high body mass index (identified as having a BMI at or above the 95th percentile)

Diabetes, Obesity and Metabolism , 26 , 16-27