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However, their wealth of pleiotropic actions soon raised expectations that they might confer benefits on non-metabolic disorders
July 20: Four years after it was rejected by the FDA due to safety concerns, Daiichi Sankyos Vanflyta (quizartinib) won approval to treat patients with acute myeloid leukemia that has a FLT3-ITD gene mutation

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Oral contraceptive efficacy may be reduced during initiation and dose escalation, based on class data from the tirzepatide SmPC
Notably, more than 30% of patients dropped out of treatment after the first month
