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"And so I think this becomes for patients much more difficult than it obviously needs to be."

Everyones journey looks a little different, so progress may come sooner for some and later for others

Int Immunopharmacol 143:113499 Yang S et al (2024a) Tirzepatide shows neuroprotective effects via regulating brain glucose metabolism in APP/PS1 mice

To make it work, you need: High protein intake Structured resistance training A mild calorie deficit (not extreme) If calories drop too low, muscle gain becomes unlikely

For women with PCOS or insulin resistance, weight loss and metabolic improvements can also lead to better mood and increased body confidence over time