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Five studies involving 825 exposed pregnancies and 592,714 comparator pregnancies evaluated first-trimester exposure and major congenital malformations

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Furthermore, studies have shown GLP-1RAs are associated with a modest decrease in intraocular pressure, particularly in individuals with elevated baseline intraocular pressure (IOP) [103], and a reduced risk of developing glaucoma in patients with T2DM [104]

The differences in the effects of GLP-1RA on tumors may be related to differences in experimental subjects, differences in inclusion and exclusion criteria, differences in experimental methods, groups, and instruments

Specificity and sensitivity of commercially available assays for glucagon-like peptide-1 (GLP-1): implications for GLP-1 measurements in clinical studies