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Their impact on inflammatory skin disorders suggests a novel therapeutic avenue

MOTS-c moves from the mitochondria into the cell nucleus under metabolic stress, where it acts on gene expression to improve how cells use glucose and fatty acids

#MASH #Hepatology #GLP1 #PharmaInsights To view or add a comment, sign in Im excited to share the recent FDA approval of Jascayd (nerandomilast), the first new oral treatment for idiopathic pulmonary fibrosis (IPF) in over a decade

of four RCTs with 176 participants demonstrated that GLP1-RAs significantly reduced waist circumference (MD: 5.16 cm), BMI (MD: 2.42 kg/m 2 ), serum triglycerides (MD: 0.20), and total testosterone levels (MD: 1.33) compared to placebo [129]

It is about losing weight more efficiently while maintaining your quality of life