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We found that GLP-1 receptor agonists were associated with a lower risk of age-related macular degeneration (especially dry AMD) in adults with diabetes and obesity compared with metformin or other weight-loss medications

Among these effects, increased insulin sensitivity, either by direct action on target organs or secondary to weight loss, might act synergistically with enhanced beta-cell function and insulin upregulation in the pancreas, collectively improving metabolic control.

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When people stopped taking one of the new weight-loss jabs they regained around 60% of their lost weight.