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First, before PSM, baseline characteristics differed significantly between groups, which could have affected the outcome analysis

While GLP-1s have been proposed to exert beneficial effects on inflammation, synaptic preservation, and microglia/astroglia function, Tan explained, it has very limited ability to cross the blood-brain barrier, where the reduction of insulin resistance in the central nervous system is really needed. In line with these sentiments, Christopher U

[14] However, individuals should be aware that rapidly increasing fibre intake can cause temporary bloating, gas, and digestive discomfort

Latin America held a 3% share of the market in 2025 and is expected to grow at a significant CAGR of 14% during the projection period, driven by GLP-1 medications that are driving structural health and economic shifts across Latin America by curbing surging obesity and type-2 diabetes rates, spurring vast biopharma investments, and fundamentally changing consumer habits in the fast-moving consumer goods sector

Aside from the advantage of having higher appeal to people who are squeamish with needles, oral formulations remove the need for cold chain storage for injectable forms of GLP1R/GIPR/GR agonists , which otherwise must be stored at cold temperatures if not provided in a dry (Tablet/pill) form