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pregnancies are unplanned. Pregnancy an exclusion criteria in trials, but pregnancies still occurred The SUSTAIN (Semaglutide Unabated Sustainability in Treatment of Type 2 Diabetes) clinical trial program, which led to the FDA approval of semaglutide for type 2 diabetes treatment, excluded women who were pregnant, breastfeeding or intending to become pregnant

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In addition, secondary analyses were performed with 1:1 nearest-neighbor propensity score matching and an exact match for baseline variables differing by 20% between cohorts for each study population

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