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Recent advances in oral drug delivery have changed that

They can help eligible patients lose weight when used appropriately

Phase 2 data has not shown significant muscle loss with retatrutide

The study also found that adults taking a GLP-1 had an increased risk for interstitial nephritis, a type of kidney condition that Al-Aly says is almost like an allergic reaction that the kidney mounts against certain drugs. He says more long-term studies are needed to better understand the risks and benefits of prolonged use

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