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46 That dedicated kidney outcomes study, involving over 3500 patients with both T2D and established chronic kidney disease, demonstrated that once-weekly subcutaneous semaglutide 1.0 mg significantly reduced the primary composite renal outcome (including kidney failure onset, a 50% persistent decline in estimated glomerular filtration rate (eGFR), or renal/cardiovascular death) compared with placebo

[Google Scholar] [5].Drucker DJ

However, even modest doses can shift your blood sugar levels enough to require dose adjustments in either medication, making close medical monitoring essential during concurrent use

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